پروپوزال انگلیسی در زمینه ژنتیک پزشکی

دسته بندي : علوم پزشکی » ژنتیک

Introduction

Aging is commonly defined as the accumulation of diverse deleterious changes occurring in cells and tissues with advancing age that are responsible for the increased risk of disease and death (Harman, 2003). The observation that most of the animals living in a natural environment rarely becomes senescent (because dying earlier for predation, disease, starvation, or drought) (Holliday 2006) suggests that aging is a phenomenon unique to the human species (Hayfl ick 2000b). In other words, the advancing knowledge of hygiene and biomedicine has led us to discover the aging process, something that was teleologically not intended for us to be experienced (Hayfl ick 2000b). The immediate consequence of the extended life expectancy is represented by the increasing number of older people in developed countries, an artefact of human civilization (Hayfl ick 1998, 2000a). Aging can be defined as an increase in the probability of death. This is how the rate of aging can be measured. Humans die not from ‘healthy’ aging but from age related diseases. Healthy aging (a late onset of disease) is associated with longevity. For example, centenarians show significant delay in the onset of age-related diseases, including cardiovascular disease, type 2 diabetes, cancer and Alzheimer’s disease.
دسته بندی: علوم پزشکی » ژنتیک

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